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These changes were not due to the limitations of the Langendorff mouse heart model as we found comparable results on analysing in vivo ischaemia in the heart using the left anterior artery, descending (LAD) occlusion model (Supplementary Fig

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Heat shock protein (Hsp) 70, the molecular chaperone that plays a critical role in CMA, is capable of recognizing and binding substrates for lysosomal degradation 48

[DOI] [PubMed] [Google Scholar] 55.Pramipexole extended release in Parkinson's disease